Shear stress blunts tubuloglomerular feedback partially mediated by primary cilia and nitric oxide at the macula densa

The present study tested whether primary cilia on macula densa serve as a flow sensor to enhance nitric oxide synthase 1 (NOS1) activity and inhibit tubuloglomerular feedback (TGF). Isolated perfused macula densa was loaded with calcein red and 4,5-diaminofluorescein diacetate to monitor cell volume...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Regul Integr Comp Physiol
Prif Awduron: Wang, Lei, Shen, Chunyu, Liu, Haifeng, Wang, Shaohui, Chen, Xinshan, Roman, Richard J., Juncos, Luis A., Lu, Yan, Wei, Jin, Zhang, Jie, Yip, Kay-Pong, Liu, Ruisheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2015
Pynciau:
Fluid and Electrolyte Homeostasis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666931/
https://ncbi.nlm.nih.gov/pubmed/26269519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00173.2015
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