Aldosterone Blunts Tubuloglomerular Feedback by Activating Macula Densa Mineralocorticoid Receptors

Chronic aldosterone administration increases glomerular filtration rate (GFR) while inhibition of mineralocorticoid receptors (MR) markedly attenuates glomerular hyperfiltration and hypertension associated with primary aldosteronism or obesity. However, the mechanisms by which aldosterone alters GFR...

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Bibliographische Detailangaben
Hauptverfasser: Fu, Yiling, Hall, John E., Lu, Deyin, Lin, Lin, Manning, R Davis, Cheng, Liang, Gomez-Sanchez, Celso E., Juncos, Luis A., Liu, Ruisheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299000/
https://ncbi.nlm.nih.gov/pubmed/22311906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.173195
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