miR-758 regulates cholesterol efflux through post-transcriptional repression of ABCA1

OBJECTIVE: The ATP-binding cassette transporter A1 (ABCA1) is a major regulator of macrophage cholesterol efflux and protects cells from excess intracellular cholesterol accumulation, however the mechanism involved in posttranscriptional regulation of ABCA1 is poorly understood. We previously showed...

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Detalhes bibliográficos
Main Authors: Ramirez, Cristina M., Dávalos, Alberto, Goedeke, Leigh, Salerno, Alessandro G., Warrier, Nikhil, Cirera-Salinas, Daniel, Suárez, Yajaira, Fernández-Hernando, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298756/
https://ncbi.nlm.nih.gov/pubmed/21885853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.232066
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