miR-27b inhibits LDLR and ABCA1 expression but does not influence plasma and hepatic lipid levels in mice

RATIONALE: Recently, there has been significant interest in the therapeutic administration of miRNA mimics and inhibitors to treat cardiovascular disease. In particular, miR-27b has emerged as a regulatory hub in cholesterol and lipid metabolism and potential therapeutic target for treating atherosc...

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Detalhes bibliográficos
Publicado no:Atherosclerosis
Main Authors: Goedeke, Leigh, Rotllan, Noemi, Ramírez, Cristina M., Aranda, Juan F., Canfrán-Duque, Alberto, Araldi, Elisa, Fernández-Hernando, Ana, Langhi, Cedric, de Cabo, Rafael, Baldán, Ángel, Suárez, Yajaira, Fernández-Hernando, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975922/
https://ncbi.nlm.nih.gov/pubmed/26520906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2015.09.033
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