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Identification of the Herboxidiene Biosynthetic Gene Cluster in Streptomyces chromofuscus ATCC 49982

The 53-kb biosynthetic gene cluster for the novel anticholesterol natural product herboxidiene was identified in Streptomyces chromofuscus ATCC 49982 by genome sequencing and gene inactivation. In addition to herboxidiene, a biosynthetic intermediate, 18-deoxy-herboxidiene, was also isolated from th...

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Bibliografiska uppgifter
Huvudupphovsmän: Shao, Lei, Zi, Jiachen, Zeng, Jia, Zhan, Jixun
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298124/
https://ncbi.nlm.nih.gov/pubmed/22247174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.06904-11
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