Identification of the Novobiocin Biosynthetic Gene Cluster of Streptomyces spheroides NCIB 11891

The novobiocin biosynthetic gene cluster from Streptomyces spheroides NCIB 11891 was cloned by using homologous deoxynucleoside diphosphate (dNDP)-glucose 4,6-dehydratase gene fragments as probes. Double-stranded sequencing of 25.6 kb revealed the presence of 23 putative open reading frames (ORFs),...

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Main Authors: Steffensky, Marion, Mühlenweg, Agnes, Wang, Zhao-Xin, Li, Shu-Ming, Heide, Lutz
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Chemistry; Biosynthesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC89847/
https://ncbi.nlm.nih.gov/pubmed/10770754
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