Biosynthetic Gene Cluster of Simocyclinone, a Natural Multihybrid Antibiotic

The entire simocyclinone biosynthetic cluster (sim gene cluster) from the producer Streptomyces antibioticus Tü6040 was identified on six overlapping cosmids (1N1, 5J10, 2L16, 2P6, 4G22, and 1K3). In total, 80.7 kb of DNA from these cosmids was sequenced, and the analysis revealed 49 complete open r...

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Detalhes bibliográficos
Main Authors: Trefzer, A., Pelzer, S., Schimana, J., Stockert, S., Bihlmaier, C., Fiedler, H.-P., Welzel, K., Vente, A., Bechthold, A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Chemistry; Biosynthesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127163/
https://ncbi.nlm.nih.gov/pubmed/11959542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1174-1182.2002
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