Biosynthetic Gene Cluster of Simocyclinone, a Natural Multihybrid Antibiotic

The entire simocyclinone biosynthetic cluster (sim gene cluster) from the producer Streptomyces antibioticus Tü6040 was identified on six overlapping cosmids (1N1, 5J10, 2L16, 2P6, 4G22, and 1K3). In total, 80.7 kb of DNA from these cosmids was sequenced, and the analysis revealed 49 complete open r...

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Bibliografiske detaljer
Main Authors: Trefzer, A., Pelzer, S., Schimana, J., Stockert, S., Bihlmaier, C., Fiedler, H.-P., Welzel, K., Vente, A., Bechthold, A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Chemistry; Biosynthesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127163/
https://ncbi.nlm.nih.gov/pubmed/11959542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1174-1182.2002
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