Biosynthetic Gene Cluster of Simocyclinone, a Natural Multihybrid Antibiotic

The entire simocyclinone biosynthetic cluster (sim gene cluster) from the producer Streptomyces antibioticus Tü6040 was identified on six overlapping cosmids (1N1, 5J10, 2L16, 2P6, 4G22, and 1K3). In total, 80.7 kb of DNA from these cosmids was sequenced, and the analysis revealed 49 complete open r...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Trefzer, A., Pelzer, S., Schimana, J., Stockert, S., Bihlmaier, C., Fiedler, H.-P., Welzel, K., Vente, A., Bechthold, A.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Assuntos:	Chemistry; Biosynthesis
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127163/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.5.1174-1182.2002
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