Biosynthetic Gene Cluster of Simocyclinone, a Natural Multihybrid Antibiotic

The entire simocyclinone biosynthetic cluster (sim gene cluster) from the producer Streptomyces antibioticus Tü6040 was identified on six overlapping cosmids (1N1, 5J10, 2L16, 2P6, 4G22, and 1K3). In total, 80.7 kb of DNA from these cosmids was sequenced, and the analysis revealed 49 complete open r...

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Bibliographic Details
Main Authors:	Trefzer, A., Pelzer, S., Schimana, J., Stockert, S., Bihlmaier, C., Fiedler, H.-P., Welzel, K., Vente, A., Bechthold, A.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology 2002
Subjects:	Chemistry; Biosynthesis
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC127163/ https://ncbi.nlm.nih.gov/pubmed/11959542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1174-1182.2002
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Biosynthetic Gene Cluster of Simocyclinone, a Natural Multihybrid Antibiotic

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