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Analysis of proteome changes in doxorubicin-treated adult rat cardiomyocyte
Doxorubicin-induced cardiomyopathy in cancer patients is well established. The proposed mechanism of cardiac damage includes generation of reactive oxygen species, mitochondrial dysfunction and cardiomyocyte apoptosis. Exposure of adult rat cardiomyocytes to low levels of DOX for 48 h induced apopto...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3298037/ https://ncbi.nlm.nih.gov/pubmed/21338723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2011.02.013 |
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