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Analysis of proteome changes in doxorubicin-treated adult rat cardiomyocyte

Doxorubicin-induced cardiomyopathy in cancer patients is well established. The proposed mechanism of cardiac damage includes generation of reactive oxygen species, mitochondrial dysfunction and cardiomyocyte apoptosis. Exposure of adult rat cardiomyocytes to low levels of DOX for 48 h induced apopto...

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Detalles Bibliográficos
Main Authors: Kumar, Suresh N., Konorev, Eugene A., Aggarwal, Deepika, Kalyanaraman, Balaraman
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298037/
https://ncbi.nlm.nih.gov/pubmed/21338723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2011.02.013
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