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Differences in Doxorubicin-Induced Apoptotic Signaling in Adult and Immature Cardiomyocytes
A proposed mechanism for cardiotoxicity of doxorubicin (DOX) involves apoptosis in cardiomyocytes. Here we investigated the molecular basis for the differences in DOX-induced toxicity in adult rat cardiomyocytes (ARCM), neonatal rat cardiomyocytes (NRCM), and rat embryonic H9c2 cardiomyoblasts. Acti...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039518/ https://ncbi.nlm.nih.gov/pubmed/18926904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.09.006 |
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