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Cytokines and LPS induce iNOS but not Enzyme Activity in Adult Rat Cardiomyocytes

There is evidence that nitric oxide (NO) formation in adult cardiomyocytes stimulated with lipopolysaccharide (LPS) does not commensurate with iNOS levels. Tetrahydrobiopterin (BH(4)) is a key factor in the stabilization and NO production by iNOS homodimer. Thus we hypothesized that BH(4) is a limit...

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書誌詳細
主要な著者: Vásquez-Vivar, Jeannette, Whitsett, Jennifer, Ionova, Irina, Konorev, Eugene, Zielonka, Jacek, Kalyanaraman, Balaraman, Shi, Yang, Pieper, Galen M.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2578873/
https://ncbi.nlm.nih.gov/pubmed/18634867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.06.017
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