Cytokines and LPS induce iNOS but not Enzyme Activity in Adult Rat Cardiomyocytes

There is evidence that nitric oxide (NO) formation in adult cardiomyocytes stimulated with lipopolysaccharide (LPS) does not commensurate with iNOS levels. Tetrahydrobiopterin (BH(4)) is a key factor in the stabilization and NO production by iNOS homodimer. Thus we hypothesized that BH(4) is a limit...

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Bibliografiska uppgifter
Huvudupphovsmän: Vásquez-Vivar, Jeannette, Whitsett, Jennifer, Ionova, Irina, Konorev, Eugene, Zielonka, Jacek, Kalyanaraman, Balaraman, Shi, Yang, Pieper, Galen M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2578873/
https://ncbi.nlm.nih.gov/pubmed/18634867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.06.017
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