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Removing technical variability in RNA-seq data using conditional quantile normalization

The ability to measure gene expression on a genome-wide scale is one of the most promising accomplishments in molecular biology. Microarrays, the technology that first permitted this, were riddled with problems due to unwanted sources of variability. Many of these problems are now mitigated, after a...

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Detalhes bibliográficos
Main Authors: Hansen, Kasper D., Irizarry, Rafael A., WU, Zhijin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297825/
https://ncbi.nlm.nih.gov/pubmed/22285995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxr054
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