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Missing data and technical variability in single-cell RNA-sequencing experiments

Until recently, high-throughput gene expression technology, such as RNA-Sequencing (RNA-seq) required hundreds of thousands of cells to produce reliable measurements. Recent technical advances permit genome-wide gene expression measurement at the single-cell level. Single-cell RNA-Seq (scRNA-seq) is...

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Détails bibliographiques
Publié dans:Biostatistics
Auteurs principaux: Hicks, Stephanie C, Townes, F William, Teng, Mingxiang, Irizarry, Rafael A
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215955/
https://ncbi.nlm.nih.gov/pubmed/29121214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxx053
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