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Binding of thrombin to subendothelial extracellular matrix. Protection and expression of functional properties.

We have analyzed the binding of thrombin, a serine protease with central roles in hemostasis, to the subendothelial extracellular matrix (ECM) produced by cultured endothelial cells. This substrate provides a thrombogenic surface where hemostasis is initiated. Binding was saturable and equilibrium w...

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Библиографические подробности
Главные авторы: Bar-Shavit, R, Eldor, A, Vlodavsky, I
Формат: Artigo
Язык:Inglês
Опубликовано: 1989
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC329765/
https://ncbi.nlm.nih.gov/pubmed/2794047
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