Binding of thrombin to subendothelial extracellular matrix. Protection and expression of functional properties.

We have analyzed the binding of thrombin, a serine protease with central roles in hemostasis, to the subendothelial extracellular matrix (ECM) produced by cultured endothelial cells. This substrate provides a thrombogenic surface where hemostasis is initiated. Binding was saturable and equilibrium w...

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Publié dans:	J Clin Invest
Auteurs principaux:	Bar-Shavit, R, Eldor, A, Vlodavsky, I
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329765/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2794047/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114272
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