Binding of thrombin to subendothelial extracellular matrix. Protection and expression of functional properties.
We have analyzed the binding of thrombin, a serine protease with central roles in hemostasis, to the subendothelial extracellular matrix (ECM) produced by cultured endothelial cells. This substrate provides a thrombogenic surface where hemostasis is initiated. Binding was saturable and equilibrium w...
Gardado en:
| Publicado en: | J Clin Invest |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1989
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329765/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2794047/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114272 |
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