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Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs.

To determine whether recombinant enkephalinase (neutral endopeptidase, EC 3.4.24.11) prevents cough induced by exogenously applied and endogenously released neuropeptides, we measured cough responses to aerosolized solutions of substance P or of capsaicin for 2 min in random-source guinea pigs befor...

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Kaydedildi:
Yayımlandı:J Clin Invest
Asıl Yazarlar: Kohrogi, H, Nadel, J A, Malfroy, B, Gorman, C, Bridenbaugh, R, Patton, J S, Borson, D B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 1989
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329719/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2474575/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114236
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