Toluene diisocyanate increases airway responsiveness to substance P and decreases airway neutral endopeptidase.

Substance P and related tachykinins contribute to the airway hyperresponsiveness caused by toluene diisocyanate (TDI) in guinea pigs. Neutral endopeptidase (NEP) is an important modulator of substance P-induced responses. To test the hypothesis that exposure to TDI would increase responsiveness to s...

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Detalhes bibliográficos
Main Authors: Sheppard, D, Thompson, J E, Scypinski, L, Dusser, D, Nadel, J A, Borson, D B
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329638/
https://ncbi.nlm.nih.gov/pubmed/2450892
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