Extracellular protons acidify osteoclasts, reduce cytosolic calcium, and promote expression of cell-matrix attachment structures.

Because metabolic acids stimulate bone resorption in vitro and in vivo, we focused on the cellular events produced by acidosis that might be associated with stimulation of bone remodeling. To this end, we exposed isolated chicken osteoclasts to a metabolic (butyric) acid and observed a fall in both...

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Detaylı Bibliyografya

Yayımlandı:	J Clin Invest
Asıl Yazarlar:	Teti, A, Blair, H C, Schlesinger, P, Grano, M, Zambonin-Zallone, A, Kahn, A J, Teitelbaum, S L, Hruska, K A
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Clinical Investigation 1989
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2547838/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114235
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