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Destabilizing Domains Derived from the Human Estrogen Receptor

Methods to rapidly and reversibly perturb the functions of specific proteins are desirable tools for studies of complex biological processes. We have demonstrated an experimental strategy to regulate the intracellular concentration of any protein of interest by using an engineered destabilizing prot...

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Autors principals: Miyazaki, Yusuke, Imoto, Hiroshi, Chen, Ling-chun, Wandless, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296833/
https://ncbi.nlm.nih.gov/pubmed/22332638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja209933r
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