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A Novel Destabilizing Domain Based on a Small-Molecule Dependent Fluorophore

Tools that can directly regulate the activity of any protein-of-interest are valuable in the study of complex biological processes. Herein, we describe the development of a novel protein domain that exhibits small molecule-dependent stability and fluorescence based on the bilirubin-inducible fluores...

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Detalles Bibliográficos
Publicado en:ACS Chem Biol
Main Authors: Navarro, Raul, Chen, Ling-chun, Rakhit, Rishi, Wandless, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992426/
https://ncbi.nlm.nih.gov/pubmed/27243964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00234
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