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Glucose and carbachol generate 1,2-diacylglycerols by different mechanisms in pancreatic islets.

Diacylglycerols (DAG) modulate secretory responses by the activation of protein kinase C. Early changes in DAG formation induced by the muscarinic receptor agonist carbachol were compared to those caused by the nutrient secretagogue glucose in pancreatic islets. Turnover rates of DAG were investigat...

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Библиографические подробности
Опубликовано в::J Clin Invest
Главные авторы: Peter-Riesch, B, Fathi, M, Schlegel, W, Wollheim, C B
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1988
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329644/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2832445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113430
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