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Glucose and carbachol generate 1,2-diacylglycerols by different mechanisms in pancreatic islets.

Diacylglycerols (DAG) modulate secretory responses by the activation of protein kinase C. Early changes in DAG formation induced by the muscarinic receptor agonist carbachol were compared to those caused by the nutrient secretagogue glucose in pancreatic islets. Turnover rates of DAG were investigat...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Peter-Riesch, B, Fathi, M, Schlegel, W, Wollheim, C B
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329644/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2832445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113430
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