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Glucose and carbachol generate 1,2-diacylglycerols by different mechanisms in pancreatic islets.

Diacylglycerols (DAG) modulate secretory responses by the activation of protein kinase C. Early changes in DAG formation induced by the muscarinic receptor agonist carbachol were compared to those caused by the nutrient secretagogue glucose in pancreatic islets. Turnover rates of DAG were investigat...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Peter-Riesch, B, Fathi, M, Schlegel, W, Wollheim, C B
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329644/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2832445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113430
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