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Glucose and carbachol generate 1,2-diacylglycerols by different mechanisms in pancreatic islets.

Diacylglycerols (DAG) modulate secretory responses by the activation of protein kinase C. Early changes in DAG formation induced by the muscarinic receptor agonist carbachol were compared to those caused by the nutrient secretagogue glucose in pancreatic islets. Turnover rates of DAG were investigat...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Peter-Riesch, B, Fathi, M, Schlegel, W, Wollheim, C B
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1988
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329644/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2832445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113430
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