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Novel ARF/p53-independent senescence pathways in cancer repression

Cellular senescence, which can be induced by various stimuli, is a stress response that manifests as irreversible cell cycle arrest. Recent studies have revealed that cellular senescence can serve as a critical barrier for cancer development. Induction of cellular senescence by oncogenic insults, su...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chan, Chia-Hsin, Gao, Yuan, Moten, Asad, Lin, Hui-Kuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296232/
https://ncbi.nlm.nih.gov/pubmed/21594579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-011-0766-y
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