Addition of insulin glargine or NPH insulin to metformin monotherapy in poorly controlled type 2 diabetic patients decreases IGF-I bioactivity similarly

AIMS/HYPOTHESIS: The aim of this study was to compare IGF-I bioactivity 36 weeks after the addition of insulin glargine (A21Gly,B31Arg,B32Arg human insulin) or NPH insulin to metformin therapy in type 2 diabetic patients who had poor glucose control under metformin monotherapy. METHODS: In the Lantu...

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Bibliographic Details
Main Authors: Varewijck, A. J., Janssen, J. A. M. J. L., Vähätalo, M., Hofland, L. J., Lamberts, S. W. J., Yki-Järvinen, H.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296010/
https://ncbi.nlm.nih.gov/pubmed/22237688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2435-7
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