Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels

The connexin 43 (Cx43) hemichannel (HC) in the mechanosensory osteocytes is a major portal for the release of factors responsible for the anabolic effects of mechanical loading on bone formation and remodeling. However, little is known about how the Cx43 molecule responds to mechanical stimulation l...

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Detalhes bibliográficos
Main Authors: Batra, Nidhi, Burra, Sirisha, Siller-Jackson, Arlene J., Gu, Sumin, Xia, Xuechun, Weber, Gregory F., DeSimone, Douglas, Bonewald, Lynda F., Lafer, Eileen M., Sprague, Eugene, Schwartz, Martin A., Jiang, Jean X.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295295/
https://ncbi.nlm.nih.gov/pubmed/22331870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115967109
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