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Direct Regulation of Osteocytic Connexin 43 Hemichannels through AKT Kinase Activated by Mechanical Stimulation

Connexin (Cx) 43 hemichannels in osteocytes are thought to play a critical role in releasing bone modulators in response to mechanical loading, a process important for bone formation and remodeling. However, the underlying mechanism that regulates the opening of mechanosensitive hemichannels is larg...

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Detalhes bibliográficos
Main Authors: Batra, Nidhi, Riquelme, Manuel A., Burra, Sirisha, Kar, Rekha, Gu, Sumin, Jiang, Jean X.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036178/
https://ncbi.nlm.nih.gov/pubmed/24563481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.550608
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