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Mechanical Strain Opens Connexin 43 Hemichannels in Osteocytes: A Novel Mechanism for the Release of Prostaglandin

Mechanosensing bone osteocytes express large amounts of connexin (Cx)43, the component of gap junctions; yet, gap junctions are only active at the small tips of their dendritic processes, suggesting another function for Cx43. Both primary osteocytes and the osteocyte-like MLO-Y4 cells respond to flu...

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Autori principali: Cherian, Priscilla P., Siller-Jackson, Arlene J., Gu, Sumin, Wang, Xin, Bonewald, Lynda F., Sprague, Eugene, Jiang, Jean X.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165395/
https://ncbi.nlm.nih.gov/pubmed/15843434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-10-0912
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