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Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons

We used in vivo amperometry to monitor changes in synaptic dopamine (DA) release in the striatum induced by overexpression of human wild-type α-synuclein in nigral DA neurons, induced by injection of an adeno-associated virus type 6 (AAV6)–α-synuclein vector unilaterally into the substantia nigra in...

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Detalhes bibliográficos
Main Authors: Lundblad, Martin, Decressac, Mickael, Mattsson, Bengt, Björklund, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295273/
https://ncbi.nlm.nih.gov/pubmed/22315428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200575109
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