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TLR4-mediated AKT Activation is MyD88/TRIF-dependent and Critical for Induction of OxPhos and Mitochondrial Transcription Factor A in Murine Macrophages

Mitochondria play a critical role in cell survival and death. Mitochondrial recovery during inflammatory processes such as sepsis is associated with cell survival. Recovery of cellular respiration, mitochondrial biogenesis and function requires coordinated expression of transcription factors encoded...

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Bibliographische Detailangaben
Hauptverfasser: Bauerfeld, Christian P., Rastogi, Ruchi, Pirockinaite, Gaila, Lee, Icksoo, Hüttemann, Maik, Monks, Bobby, Birnbaum, Morris J., Franchi, Luigi, Nuñez, Gabriel, Samavati, Lobelia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294201/
https://ncbi.nlm.nih.gov/pubmed/22312125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102157
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