TLR4-mediated AKT Activation is MyD88/TRIF-dependent and Critical for Induction of OxPhos and Mitochondrial Transcription Factor A in Murine Macrophages

Mitochondria play a critical role in cell survival and death. Mitochondrial recovery during inflammatory processes such as sepsis is associated with cell survival. Recovery of cellular respiration, mitochondrial biogenesis and function requires coordinated expression of transcription factors encoded...

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Autori principali: Bauerfeld, Christian P., Rastogi, Ruchi, Pirockinaite, Gaila, Lee, Icksoo, Hüttemann, Maik, Monks, Bobby, Birnbaum, Morris J., Franchi, Luigi, Nuñez, Gabriel, Samavati, Lobelia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294201/
https://ncbi.nlm.nih.gov/pubmed/22312125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102157
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