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Bone Marrow p16(INK4a)-Deficiency Does Not Modulate Obesity, Glucose Homeostasis or Atherosclerosis Development

OBJECTIVE: A genomic region near the CDKN2A locus, encoding p16(INK4a), has been associated to type 2 diabetes and atherosclerotic vascular disease, conditions in which inflammation plays an important role. Recently, we found that deficiency of p16(INK4a) results in decreased inflammatory signaling...

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Detalhes bibliográficos
Main Authors: Wouters, Kristiaan, Cudejko, Céline, Gijbels, Marion J. J., Fuentes, Lucia, Bantubungi, Kadiombo, Vanhoutte, Jonathan, Dièvart, Rebecca, Paquet, Charlotte, Bouchaert, Emmanuel, Hannou, Sarah Anissa, Gizard, Florence, Tailleux, Anne, de Winther, Menno P. J., Staels, Bart, Paumelle, Réjane
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293804/
https://ncbi.nlm.nih.gov/pubmed/22403661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032440
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