The tumour suppressor CDKN2A/p16(INK4a) regulates adipogenesis and bone marrow-dependent development of perivascular adipose tissue

The genomic CDKN2A/B locus, encoding p16(INK4a) among others, is linked to an increased risk for cardiovascular disease and type 2 diabetes. Obesity is a risk factor for both cardiovascular disease and type 2 diabetes. p16(INK4a) is a cell cycle regulator and tumour suppressor. Whether it plays a ro...

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Detalhes bibliográficos
Publicado no:Diab Vasc Dis Res
Main Authors: Wouters, Kristiaan, Deleye, Yann, Hannou, Sarah A, Vanhoutte, Jonathan, Maréchal, Xavier, Coisne, Augustin, Tagzirt, Madjid, Derudas, Bruno, Bouchaert, Emmanuel, Duhem, Christian, Vallez, Emmanuelle, Schalkwijk, Casper G, Pattou, François, Montaigne, David, Staels, Bart, Paumelle, Réjane
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652646/
https://ncbi.nlm.nih.gov/pubmed/28868898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1479164117728012
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