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Systemic Delivery of siRNA via LCP Nanoparticle Efficiently Inhibits Lung Metastasis

Targeted delivery remains the major challenge for the application of small interfering RNA (siRNA). We have developed a lipid/calcium/phosphate (LCP) nanoparticle (NP) to improve siRNA delivery efficiency. The LCP NP was prepared by using microemulsion technology to form calcium/phosphate (CaP) core...

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Bibliografiske detaljer
Main Authors: Yang, Yang, Li, Jun, Liu, Feng, Huang, Leaf
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293613/
https://ncbi.nlm.nih.gov/pubmed/22186791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.270
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