Improved siRNA Delivery Efficiency via Solvent-Induced Condensation of Micellar Nanoparticles

Efficient delivery of siRNA remains one of the primary challenges of RNA interference therapy. PEGylated polycationic carriers have been widely used for the condensation of DNA and RNA molecules into complex-core micelles. The PEG corona of such nanoparticles can significantly improve their colloida...

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Bibliographic Details
Published in:Nanotechnology
Main Authors: Wu, Juan, Qu, Wei, Williford, John-Michael, Ren, Yong, Jiang, Xuesong, Jiang, Xuan, Pan, Deng, Mao, Hai-Quan, Luijten, Erik
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790992/
https://ncbi.nlm.nih.gov/pubmed/28266928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1361-6528/aa6519
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