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Enhanced Stability and Knockdown Efficiency of Poly(ethylene glycol)- polyphosphoramidate/siRNA Micellar Nanoparticles by Co-condensation with Sodium Triphosphate
PURPOSE: Polyelectrolyte complex nanoparticles are a promis ing vehicle for siRNA delivery but suffer from low stability under physiological conditions. An effective stabilization meth od is essential for the success of polycationic nanoparticle mediated siRNA delivery. In this study, sodium triphos...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4030395/ https://ncbi.nlm.nih.gov/pubmed/21387148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0408-7 |
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