Development of a docetaxel micellar formulation using poly(ethylene glycol)–polylactide–poly(ethylene glycol) (PEG–PLA–PEG) with successful reconstitution for tumor targeted drug delivery

Docetaxel (DTX)-loaded polymeric micelles (DTBM) were formulated using the triblock copolymer, poly(ethylene glycol)–polylactide–poly(ethylene glycol) (PEG–PLA–PEG), to comprehensively study their pharmaceutical application as anticancer nanomedicine. DTBM showed a stable formulation of anticancer n...

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Autors principals: Taehoon Sim, Jae Eun Kim, Ngoc Ha Hoang, Jin Kook Kang, Chaemin Lim, Dong Shik Kim, Eun Seong Lee, Yu Seok Youn, Han-Gon Choi, Hyo-Kyung Han, Kwon-Yeon Weon, Kyung Taek Oh
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis Group 2018-01-01
Col·lecció:Drug Delivery
Matèries:
nanomedicine
lyophilization
cancer
reconstitution
polymeric micelle
Accés en línia:http://dx.doi.org/10.1080/10717544.2018.1477865
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