Improved siRNA Delivery Efficiency via Solvent-Induced Condensation of Micellar Nanoparticles

Efficient delivery of siRNA remains one of the primary challenges of RNA interference therapy. PEGylated polycationic carriers have been widely used for the condensation of DNA and RNA molecules into complex-core micelles. The PEG corona of such nanoparticles can significantly improve their colloida...

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Pubblicato in:Nanotechnology
Autori principali: Wu, Juan, Qu, Wei, Williford, John-Michael, Ren, Yong, Jiang, Xuesong, Jiang, Xuan, Pan, Deng, Mao, Hai-Quan, Luijten, Erik
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790992/
https://ncbi.nlm.nih.gov/pubmed/28266928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1361-6528/aa6519
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