טוען...
Intravenous Delivery of siRNA Targeting CD47 Effectively Inhibits Melanoma Tumor Growth and Lung Metastasis
CD47 is a “self marker” that is usually overexpressed on the surface of cancer cells to enable them to escape immunosurveillance. Recognition of CD47 by its receptor, signal regulatory protein α (SIRPα), which is expressed in the macrophages, inhibits phagocytic destruction of cancer cells by the ma...
שמור ב:
Main Authors: | , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
Nature Publishing Group
2013
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3808133/ https://ncbi.nlm.nih.gov/pubmed/23774794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.135 |
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