Concomitant Intravenous Nitroglycerin With Intracoronary Delivery of AAV1.SERCA2a Enhances Gene Transfer in Porcine Hearts

SERCA2a gene therapy improves contractile and energetic function of failing hearts and has been shown to be associated with benefits in clinical outcomes, symptoms, functional status, biomarkers, and cardiac structure in a phase 2 clinical trial. In an effort to enhance the efficiency and homogeneit...

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Autori principali: Karakikes, Ioannis, Hadri, Lahouaria, Rapti, Kleopatra, Ladage, Dennis, Ishikawa, Kiyotake, Tilemann, Lisa, Yi, Geng-Hua, Morel, Charlotte, Gwathmey, Judith K, Zsebo, Krisztina, Weber, Thomas, Kawase, Yoshiaki, Hajjar, Roger J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293603/
https://ncbi.nlm.nih.gov/pubmed/22215018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.268
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