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Safety and long-term efficacy of AAV1.SERCA2a using nebulizer delivery in a pig model of pulmonary hypertension
Nebulization delivery of adeno-associated virus serotype 1 encoding sarcoplasmic reticulum Ca(2+)-ATPase2a (AAV1.SERCA2a) gene was examined in a Yukatan miniature swine model of chronic pulmonary hypertension (n = 13). Nebulization of AAV1.SERCA2a resulted in homogenous distribution of vectors, lowe...
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| Publicado no: | Pulm Circ |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6146327/ https://ncbi.nlm.nih.gov/pubmed/30129881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894018799738 |
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