Amyloid-β Oligomers Induce Differential Gene Expression in Adult Human Brain Slices

Cognitive decline in Alzheimer disease (AD) is increasingly attributed to the neuronal impact of soluble oligomers of the amyloid-β peptide (AβOs). Current knowledge on the molecular and cellular mechanisms underlying the toxicity of AβOs stems largely from rodent-derived cell/tissue culture experim...

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Dades bibliogràfiques
Autors principals: Sebollela, Adriano, Freitas-Correa, Leo, Oliveira, Fabio F., Paula-Lima, Andrea C., Saraiva, Leonardo M., Martins, Samantha M., Mota, Louise D., Torres, Cesar, Alves-Leon, Soniza, de Souza, Jorge M., Carraro, Dirce M., Brentani, Helena, De Felice, Fernanda G., Ferreira, Sergio T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Neurobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293600/
https://ncbi.nlm.nih.gov/pubmed/22235132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.298471
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