Llwytho...

Biophysical and Mechanistic Insights into Novel Allosteric Inhibitor of Spleen Tyrosine Kinase

Extracellular stimulation of the B cell receptor or mast cell FcϵRI receptor activates a cascade of protein kinases, ultimately leading to antigenic or inflammation immune responses, respectively. Syk is a soluble kinase responsible for transmission of the receptor activation signal from the membran...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hall, Justin, Aulabaugh, Ann, Rajamohan, Francis, Liu, Shenping, Kaila, Neelu, Wan, Zhao-Kui, Ryan, Mark, Magyar, Rachelle, Qiu, Xiayang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293529/
https://ncbi.nlm.nih.gov/pubmed/22219190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311993
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!