Unique domain appended to vertebrate tRNA synthetase is essential for vascular development

New domains were progressively added to cytoplasmic aminoacyl transfer RNA (tRNA) synthetases during evolution. One example is the UNE-S domain, appended to seryl-tRNA synthetase (SerRS) in species that developed closed circulatory systems. Here we show using solution and crystal structure analyses...

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Huvudupphovsmän: Xu, Xiaoling, Shi, Yi, Zhang, Hui-Min, Swindell, Eric C., Marshall, Alan G., Guo, Min, Kishi, Shuji, Yang, Xiang-Lei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Pub. Group 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293412/
https://ncbi.nlm.nih.gov/pubmed/22353712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1686
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