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The BRAF(V600E) causes widespread alterations in gene methylation in the genome of melanoma cells

Although BRAF(V600E) is well known to play an important role in the tumorigenesis of melanoma, its molecular mechanism, particularly the epigenetic aspect, has been incompletely understood. Here, we investigated the role of BRAF(V600E) signaling in altering gene methylation in the genome of melanoma...

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Bibliografski detalji
Glavni autori: Hou, Peng, Liu, Dingxie, Dong, Jianli, Xing, Mingzhao
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293379/
https://ncbi.nlm.nih.gov/pubmed/22189819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.2.18707
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