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Genome-wide alterations in gene methylation by the BRAF V600E mutation in papillary thyroid cancer cells

The BRAF V600E mutation plays an important role in the tumorigenesis of papillary thyroid cancer (PTC). To explore an epigenetic mechanism involved in this process, we performed a genome-wide DNA methylation analysis using a methylated CpG island amplification (MCA)/CpG island microarray system to e...

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Autori principali: Hou, Peng, Liu, Dingxie, Xing, Mingzhao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346957/
https://ncbi.nlm.nih.gov/pubmed/21937738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-11-0212
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